Where Am I? -> WP 3 - Survival -> EUROlinkCAT Results Explorer: Survival
Direct link to this page: http://www.EUROlinkCAT.eu/wp3-survival/eurolinkcatresultsexplorersurvival

EUROlinkCAT Results Explorer: Interactive tool for visualising the survival of children born with congenital anomalies up to 10 years of age

This interactive survival plots tool is designed to allow you to visualise and compare survival between different anomaly groups. In addition you can look at different birth cohorts, multiple malformation status and by singleton versus singleton and multiple births. Each survival curve is displayed in separate colours with details in the legend.

>>Click here to access the EUROlinkCAT Results Explorer: Survival<<

Congenital Anomaly Options

There are three tabs:

  • Common Anomalies – This lists 38 different anomalies: 34 are from those anomaly groups specified in the EUROCAT Guide 1.4 which are amongst the most frequent congenital anomalies and an additional 4 are for Down syndrome with and without CHD or gastrointestinal anomalies
  • Rare anomalies and Genetic Syndromes – This lists 47 different anomalies: 26 are from those anomaly groups specified in the EUROCAT Guide 1.4 that are less frequent than those in the “Common Anomalies” table and an additional 21 are for specific congenital anomalies / syndromes currently not defined as sub groups in EUROCAT Guide 1.4.
  • Custom Selection – This lists all 85 different anomalies and enables more choices in which anomalies can be selected and plotted at the same time. For example this enables the same anomaly to be plotted over two different time periods. 

Birth cohort options

There are separate selections available for:

  • 1995-2014 – Births in 1995-2014 (the default option)
  • 1995-2004 – Births in 1995-2004
  • 2005-2014 – Births in 2005-2014

Multiple Malformation options

There are separate selections available for:

  • Isolated - Births with an isolated anomaly only (the default option)
  • Mult excl – Births with an isolated anomaly and births with two or more major anomalies of different organ systems, excluding sequences, chromosomal and monogenic syndromes
  • Mult incl - Births with an isolated anomaly and births with two or more major anomalies of different organ systems, including sequences, chromosomal and monogenic syndromes

 Multiple birth options

There are separate selections available for:

  • Singletons - Singleton births only (the default option)
  • Sing+Mult - Singleton and multiple births combined


Display Options

  • Include 95% CI – shows the 95% confidence interval as dashed lines
  • Auto scale Y axis – the default Y axis (Proportion surviving) scaling is from 0 to 1. Selecting this option alters the Y axis to make use of more of the plot area.
  • Smooth line – this option alters the plot from a stepped survival curve to a smooth line
  • Enforce same registries in selection – the default is selected and this option controls whether the available selections are from the same registries as those included in the first anomaly group selected. If this option is selected then unavailable selections are automatically disabled. Care needs to be taken when comparing survival between different groups of registries.
  • Degree of heterogeneity (I2) and medians year 1, years 2-10 – If this is selected then the plots are automatically displayed as smooth lines. The median I2 values for year 1 and for years 2-10 are added to the legend. Data points are annotated with a bullet point for moderate values between 50 and 75% and diamonds for I2 greater than 75%. The I2 value indicates the percentage of variance in a meta-analysis that is attributable to study heterogeneity.


Additional Information

  • Show Registry and Population details - For each anomaly selected, the registries that have provided data on the survival of births with that anomaly, are listed together with the total number of births in the population covered. If the option “Enforce same registries in selection” is ticked this information will be provided only once for all anomalies as all survival curves are based on data from the same registers.


Contact for Further Information

EUROlinkCAT is keen to encourage the use of the data displayed.

Please contact us using the details provided on the Contact Information & Data Requests page if you wish to discuss potential research projects using the data illustrated here.